PETACH TIKVA, Israel, June 17, 2014 /PRNewswire/ — Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (CFBI.TA), a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced today it has finalized enrollment in its Phase II/III trial of CF101 for the treatment of psoriasis with over 300 patients through 17 clinical centers in the U.S., Israel and Europe. Top line results from the trial are expected in the first quarter of 2015.

The psoriasis therapeutic market was worth $3.6 billion in 2010 and is forecast to grow to $6.7 billion by 2018, according to Global Data. The market is dominated by biological drugs that are primarily administered via intravenous injection (IV) and have potential side effects.

“Based on our studies to date, we believe that, if approved, CF101 would have the potential to offer an oral, safe and well-tolerated treatment alternative for people living with psoriasis,” stated Can-Fite CEO Dr. Pnina Fishman. “Now that we have completed patient enrollment, we hope that the upcoming conclusion of this Phase II/III trial will yield additional data which may prove the efficacy of CF101 in the treatment of psoriasis.”

About the Trial

The Phase II/III double-blind, placebo-controlled study is designed to test the efficacy of CF101 in 300 patients with moderate-to-severe plaque psoriasis. The first study cohort was comprised of three arms with patients receiving: 1 mg of CF101; 2 mg of CF101; and placebo. All patients receiving placebo were switched to either 1 mg or 2 mg of CF101 after 12 weeks. The primary efficacy endpoints are a statistically significant improvement in standard measures used by dermatologists to assess psoriasis including the Psoriasis Area Sensitivity Index (PASI) score and the Physicians’ Global Assessment (PGA) score as well as various safety parameters.

Interim safety and efficacy results were released from the first 103 patients who completed 24 weeks of treatment in the trial. The positive clinical effects of CF101 at the 2 mg dose relative to placebo were observed through PASI and PGA scores, with the responses accumulating steadily over the 24-week treatment period. To allow the trial to meet its full objectives, the study protocol has been amended to enroll patients for the 2 mg dose and placebo administration for an extended study period of 32 weeks.

HAIFA, Israel, June 19, 2014 (GLOBE NEWSWIRE) — Pluristem Therapeutics Inc. (PSTI) (TASE:PLTR), a leading developer of placenta-based cell therapies, today announced that Russia’s Federal Service for Intellectual Property has granted to Pluristem Patent No. 2515156 titled, “Methods of Treating Inflammatory Colon Diseases”. The patent covers methods for treating ulcerative colitis or Crohn’s disease using placenta-derived cells. This patent has already been issued to Pluristem in South Africa and is currently pending in several other jurisdictions.

“Pre-clinical studies have demonstrated that PLX cells are potentially effective in treating inflammatory bowel disease, and we may consider advancing into clinical trials with this indication in future,” stated Pluristem CEO Zami Aberman. “This patent issued in Russia is the latest in a series of patents we’ve been granted across the globe for the use of placenta-derived cell therapies in a variety of different indications.”

About Pluristem Therapeutics

Pluristem Therapeutics Inc. is a leading developer of placenta-based cell therapies. The Company’s patented PLX (PLacental eXpanded) cells are a protein delivery platform that releases a cocktail of therapeutic proteins in response to a host of local and systemic inflammatory and ischemic conditions. PLX cells are grown using the Company’s proprietary 3D micro-environmental technology and are an “off-the-shelf” product that requires no tissue matching prior to administration.

Pluristem has a strong intellectual property position, Company-owned GMP certified manufacturing and research facilities, strategic relationships with major research institutions and a seasoned management team. For more information visit www.pluristem.com, the content of which is not part of this press release.

HAIFA, Israel, June 16, 2014 (GLOBE NEWSWIRE) — Pluristem Therapeutics Inc. (PSTI) (TASE:PLTR), a leading developer of placenta-based cell therapies, today announced it has been granted Patent No. 261087 from India’s Office of the Controller General of Patents, Designs & Trade Marks for a patent titled, “Methods for Cell Expansion and Conditioned Media Produced Thereby for Therapy.”

The patent, which has also been granted to Pluristem in Australia, Russia and South Africa, covers the Company’s key technology platform, its method for 3-dimensional expansion of placental and adipose (fat) derived cells. It also covers the composition of cells derived using this method.

“We believe Pluristem is the global leader in the commercial-scale production of placenta-derived cells. In our manufacturing facility, we use proprietary 3-dimensional cell expansion technology that gives us the ability to precisely control cell growth based on the intended indication to be treated. Our ability to do this on a large scale is one of our key assets,” stated Pluristem CEO Zami Aberman.

“This patent issued by India is an important part of our global IP strategy to protect our breakthrough cell production methods in high-value and emerging healthcare markets where we see future potential for growth,” Aberman added.

About Pluristem Therapeutics

Pluristem Therapeutics Inc. is a leading developer of placenta-based cell therapies. The Company’s patented PLX (PLacental eXpanded) cells are a drug delivery platform that releases a cocktail of therapeutic proteins in response to a host of local and systemic inflammatory and ischemic diseases. PLX cells are grown using the Company’s proprietary 3D micro-environmental technology and are an “off-the-shelf” product that requires no tissue matching prior to administration.

Pluristem has a strong intellectual property position, Company-owned GMP certified manufacturing and research facilities, strategic relationships with major research institutions and a seasoned management team. For more information visit www.pluristem.com, the content of which is not part of this press release.

EVEN YEHUDA, Israel, June 11, 2014 /PRNewswire/ —

Bluesphere Corp. (BLSP) (the “Company” or “Bluesphere”), a clean energy company that develops, manages and owns waste-to-energy projects, announced today it is pursuing a strategy to acquire fully operational, revenue generating waste-to-energy facilities in select global markets. The Company is augmenting its current build-own-operate model with an acquirer-own-operate strategy in order to create immediate revenue and cash flow generation, putting the Company on a short term path to profitability in the $6 billion global waste-to-energy market.

Bluesphere is currently conducting due diligence on an acquisition opportunity in Italy for 16 anaerobic digestion waste-to-energy 1 MW facilities that have each been fully operational for at least a year. These facilities have long term agreements with local utilities that are purchasing electricity from the plants. Based on due diligence conducted to date, collectively the plants are producing very high EBITDA, are expected to have an internal rate of return (IRR) of greater than 25%, and if acquired, would generate strong immediate cash for Bluesphere.

“By executing on this acquisition strategy, we believe we are accelerating our timeline to significant revenues, EBITDA and profitability, while also reducing risk by acquiring facilities that have a track record of consistent operational performance. The acquisition opportunity in Italy serves as model for Bluesphere’s future acquisitions as we pursue a tremendous global opportunity in the organic waste-to-energy market,” stated Bluesphere CEO Shlomi Palas.

Bluesphere is currently developing two facilities in the U.S. under its build-own-operate model. The first is a 5.2 MW facility in Charlotte, North Carolina slated to become fully operational in 2015. Approximately $23 million in project financing has been secured from a Fortune 50 company and a leading environmental finance fund. One of the largest power holding companies in the U.S. has signed a long-term contract with Bluesphere to purchase electricity generated at the Charlotte plant.

About Bluesphere Corporation

Bluesphere Corporation is a company in the cleantech sector as a waste-to-energy project integrator. Bluesphere develops waste-to-energy and other renewable energy projects. The Company aspires to become a key player in the global waste-to-energy and renewable energy markets. For further information please visit the Company’s website http://www.bluespherecorporate.com

VIENNA, Va.–(BUSINESS WIRE)–

CEL-SCI Corporation (NYSE MKT: CVM) today announced that during the month of May the Company enrolled 14 patients with advanced primary, not yet treated, head and neck cancer into its global pivotal Phase III head and neck cancer trial for its investigational immunotherapy Multikine* (Leukocyte Interleukin, Injection). A total of 49 patients were enrolled over the past three months, with 14 patients enrolled in March, 21 in April, and 14 in May of 2014. This marks a continued increase over the prior three month period when a total of 18 patients had been enrolled, with 4 enrolled in December 2013, 8 in January, and 6 in February 2014.

“While there may be monthly variations, we are seeing a general trend of rapidly increasing enrollment through the support of our new CROs, Ergomed and Aptiv Solutions, the addition of new centers, and a definite increase in interest by investigators in enrolling patients in our study. As we continue to expand the study to more centers in more countries, we expect to see continued increase in the rate of enrollment in this Phase III trial,” stated CEL-SCI Chief Executive Officer Geert Kersten.

So far, a total of 197 patients have been enrolled in the study. The study is expected to complete enrollment of 880 patients by the end of 2015.

About Multikine Phase III Study

The Multikine Phase III study is enrolling patients with advanced primary, not yet treated, head and neck cancer. The objective of the study is to demonstrate a statistically significant improvement in the overall survival of enrolled patients who are treated with the Multikine treatment regimen plus Standard of Care (SOC) vs. subjects who are treated with SOC only.

About Multikine

Multikine (Leukocyte Interleukin, Injection) is an investigational immunotherapeutic agent that is being tested in an open-lable, randomized, controlled, global pivotal Phase III clinical trial as a potential first-line treatment for advanced primary head and neck cancer. If approved for use following completion of CEL-SCI’s clinical development program for head and neck cancer, Multikine would be a different type of therapy in the fight against cancer; one that appears to have the potential to work with the body’s natural immune system in the fight against tumors. CEL-SCI is aiming to complete enrollment of subjects to the Phase III head and neck cancer study by the end of 2015. The trial is expected to expand into a total of approximately 100 clinical centers in about 20 countries.

In October 2013, CEL-SCI announced that it had signed a CRADA (Cooperative Research and Development Agreement) with the U.S. Naval Medical Center, San Diego, to develop Multikine as a potential treatment for HIV/HPV co-infected men and women with peri-anal warts. CEL-SCI also announced that it entered into two new co-development agreements with Ergomed to further clinically develop Multikine for cervical dysplasia/neoplasia in women who are co-infected with HIV and HPV and for peri-anal warts in men and women who are co-infected with HIV and HPV.

VIENNA, Va.–(BUSINESS WIRE)–

CEL-SCI Corporation (NYSE MKT:CVM) today announced that the United Kingdom’s Medicines and Healthcare Products Regulatory Agency (MHRA) has granted regulatory approval to begin the Company’s Phase III Head and Neck Cancer clinical trial of its investigational cancer immunotherapy treatment Multikine* (Leukocyte Interleukin, Injection) in the United Kingdom (UK). The UK becomes the 13th country to join the trial. Several hospitals and medical clinics in the UK are expected to participate in the Phase III trial for the treatment of head and neck cancer.

“Patients and doctors alike are increasingly aware of the potential promise of immunotherapy in the fight against cancer. Approximately 200 patients are already enrolled in this Phase III study with Multikine and our goal is to have a total of 880 patients enrolled worldwide by the end of 2015,” stated CEL-SCI Chief Executive Officer Geert Kersten.

Further expansion of the trial is underway with a goal to have a total of about 100 clinical centers through 20 countries by the end of 2015.

About Multikine Phase III Study

The Multikine Phase III study (the IT-MATTERS Study) is enrolling patients with advanced primary, not yet treated, head and neck cancer. The objective of the study is to demonstrate a statistically significant improvement in overall survival of enrolled patients who are treated with the Multikine treatment regimen plus Standard of Care (SOC) vs. subjects who are treated with SOC only.

About Multikine

Multikine (Leukocyte Interleukin, Injection) is an immunotherapeutic agent that is being tested in a randomized, controlled, global pivotal Phase III clinical trial as a potential first-line treatment for advanced primary head and neck cancer. If approved for use by the US FDA or other Regulatory agencies following completion of CEL-SCI’s clinical development program for head and neck cancer, Multikine would be a different type of therapy in the fight against cancer; one that appears to have the potential to work with the body’s natural immune system in the fight against tumors. CEL-SCI is aiming to complete enrollment of subjects to the Phase III head and neck cancer study by the end of 2015. The trial is expected to expand into a total of approximately 100 clinical centers in about 20 countries.

In October 2013, CEL-SCI announced that it had signed a CRADA (Cooperative Research and Development Agreement) with the US Naval Medical Center, San Diego, to develop Multikine as a potential treatment for HIV/HPV co-infected men and women with peri-anal warts. CEL-SCI also announced that it entered into two new co-development agreements with Ergomed to further clinically develop Multikine for cervical dysplasia/neoplasia in women who are co-infected with HIV and HPV and for peri-anal warts in men and women who are co-infected with HIV and HPV.

EVEN YEHUDA, Israel, June 2, 2014 /PRNewswire/ —

Bluesphere Corp. (BLSP) (the “Company” or “Bluesphere”), a clean energy company that develops, manages and owns waste-to-energy projects, announced today that Mecklenburg County has issued the Company an air emissions permit for its 5.2 MW waste-to-energy project in Charlotte, North Carolina. Obtaining the air emissions permit is a requirement prior to build-out and operations at the plant. The permit signifies that the 5.2 MW waste-to-energy plant meets stringent local, regional and national environmental emissions regulations.

“This marks another milestone in the development of our 5.2 MW clean energy project in Charlotte. The air permit usually tends to be one of the more difficult-to-get permits. We are now preparing to submit applications for the remaining permits, but the biggest piece of the permitting process is now behind us,” stated Bluesphere CEO Shlomi Palas. “We are nearing ground-breaking on the site and will produce and deliver power on schedule.”

Bluesphere is the project owner, developer and manager for this 5.2 MW organics-to-energy anaerobic digester. The facility will intake organic waste such as food and farm waste that would normally go into landfills. The organic waste is processed in an anaerobic digester to emit biogas, which then is turned into electricity and compost is a by-product. The facility generates revenues from intake of organic waste, as well as the sale of clean, renewable electricity, and the sale of compost.

A Fortune 50 company has signed on to provide over $14 million in debt project financing for the facility and a leading environmental finance fund will provide equity project financing of $8.0 million, with an additional $1.5 million to be kept in reserve. One of the largest power holding companies in the U.S. has signed a long-term contract with Bluesphere to purchase electricity generated at the Charlotte plant. Compost, which is a by-product of the organics-to-energy generation process, will be purchased under a contractual agreement by one of the largest privately held composting companies in the world.

Bluesphere is developing its second U.S. organics-to-waste facility in Rhode Island and by 2018 the Company plans to have 11 facilities built with 6 more under construction and development.

Waste-to-energy is one of the fastest growing segments in the renewable energy markets. According to SBI Energy, the thermal and biological segments reached $6 billion in 2012 and will reach $29 billion by 2022.

VIENNA, Va.–(BUSINESS WIRE)–

CEL-SCI Corporation (NYSE MKT:CVM) today announced that the University of Cincinnati Cancer Institute is the latest medical center in the U.S. to join its Phase III head and neck cancer clinical trial of its investigational cancer immunotherapy treatment Multikine* (Leukocyte Interleukin, Injection). CEL-SCI’s study is already active in dozens of clinical centers in 12 countries and is expected to expand to a total of 20 countries with an estimated 880 patients to be enrolled by the end of 2015. According to the American Society of Clinical Oncology, head and neck cancers account for about 3% to 5% of all cancers in the United States.

The University of Cincinnati’s Comprehensive Head and Neck Cancer Center offers patient-centered care from a multidisciplinary team that focuses exclusively on treating cancers of the head and neck. This includes cancers of the oral cavity (tongue, jaw, lip, cheek, and hard palate), throat (tonsil, and base of tongue), larynx (voice box), nose and sinus cavity, skull base, salivary glands, thyroid gland and parathyroid gland. The clinical team includes head and neck cancer surgeons, radiation oncologists, medical oncologists, head and neck radiologists, pathologists, speech therapists and experienced head and neck cancer nurses.

Dr. Keith Casper, Co-Director of the Comprehensive Head and Neck Cancer Center, is the Principal Investigator of CEL-SCI’s Phase III trial at the University of Cincinnati. Dr. Casper has been a Head and Neck Surgical Oncologist at UC Health since 2009. He is also an Assistant Professor of Otolaryngology- Head and Neck Surgery at the University of Cincinnati College of Medicine.

“The University of Cincinnati Cancer Institute’s Comprehensive Head and Neck Cancer Center is one of the largest centers in its region specialized in head and neck cancer. Dr. Casper is a renowned expert and thought leader in head and neck cancer and we are very pleased to have his participation in our global study,” stated CEL-SCI Chief Executive Officer Geert Kersten.

To read the entire article please visit the following link: http://www.energycentral.com/enduse/energyefficiency/articles/2913/Fast-Food-Industry-Can-Become-Fastest-Growing-Player-in-Clean-Energy

Pompano Beach, Fla., May 21, 2014 (GLOBE NEWSWIRE) — DS Healthcare Group, Inc.(DSKX), a leading developer of personal care products and specialty pharmaceuticals, today announced it has appointed Dr. Brijeshkumar Patel, PhD to the newly created position of Director of Research and Development. In this role Dr. Patel will focus on the development of transdermal drug delivery systems for the Company’s hair-care products, as well as restructuring existing and new molecules for increased absorption and effectiveness. He will work alongside a team of chemists both within DS Healthcare and with the Company’s external consultants to develop skin-care applications. In addition to maintaining the highest quality controls for the Company’s over-the-counter formulations, Dr. Patel will also collaborate with Aptiv Solutions, DS Healthcare’s clinical research organization (CRO) on the Company’s prescription-grade hair formulation currently under development.

“We are executing on the pursuit of science that enhances hair regrowth and youthful skin. Dr. Patel joins us as Director of R&D to lead our clinical development efforts for both our prescription hair loss development program and our portfolio of over-the-counter hair care and skin care products,” stated DS Healthcare President and CEO Daniel Khesin. “We’ve seen demand for our over-the-counter products continue to grow based on the performance of our proprietary, patent-pending formulations. With Dr. Patel on our team, we believe we will be in a position to accelerate our innovation and clinical programs with a goal towards expanding our intellectual property, product portfolio and corresponding revenues.”

Dr. Patel has over 7 years of research experience in developing novel drug delivery systems for pulmonary, oral and topical delivery of small molecules and peptide drugs. He brings to DS Healthcare specific expertise in designing preclinical and clinical study protocols. He has authored 10 articles published in peer-reviewed scientific publications and delivered over a dozen poster and oral presentations at scientific conferences. Dr. Patel received his Ph.D. in Pharmaceutical Sciences from the Graduate School of Biomedical Sciences, Texas Tech University Health Sciences Center. He also earned his M.S. in Pharmaceutical Sciences from the School of Pharmacy, Campbell University, and his B.S. in Pharmaceutical Sciences from the Shri B M Shah College of Pharmaceutical Education and Research, HNGU, India.

DS Healthcare Group recently announced its intention to file an Investigational New Drug application with the U.S. Food and Drug Administration for a topical hair loss treatment. If approved, it would be the third FDA-approved treatment for hair loss and only the second topical treatment. The Company has recently filed two patents for its prescription and over-the-counter hair loss formulations.

About DS Healthcare Group

DS Healthcare Group Inc. leads in the development of biotechnology for topical therapies. It markets through online and specialty retailers, distributors, cosmetics wholesalers, and salons. Its research has led to a highly innovative portfolio of personal care products and additional innovations in pharmaceutical projects. For more information on DS Healthcare Group’s flagship brand, visit www.dslaboratories.com